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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c94a7b3343a298f86b29ab6107402440b7f09b1c2d1bac73ce7bacf11f97b9c' 
  AND token = 'AmnAx1e4GUSuewFT0KhiNoXd9nWRB/fvDXp3LaMn+qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}