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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10721ea8801ae57a040101b24e4effced0058f477d828ca34d995016a54f5990' 
  AND token = 'GlhE972sPuvraOCOmRmxLXc9gxP5Kzcoz0OHg+KdYv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}