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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cfc2bdd6e57d89007e0953de77758541c9b0f180782242f3fb3fe1b18a8c66a' 
  AND token = 'rfIRlNJnpK9TJ1zeGAMF/+DJ2lVqzxVOcNXdriyLiQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}