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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c791275396a3061a9053e15a24038bf131fdf0e5cb33a8e448134999701bf1' 
  AND token = 'RnRwXlMAPOUas0rRCfqCAP/NC28SQVU9yjcCk2Gl+lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}