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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca5d3771e5a54464ca5b617e7279b030d687d9564676e7101abcb70886f7159' 
  AND token = 'ICu9/vWPrR0jHdSLmqgl1XGAYuu0B8tWVQ3sRrlBi1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}