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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'baa3082af13852cb52a33000d15a2691a202c0cd21a3bf6d45110d4a2940bb12' 
  AND token = 'BUIupN9uhG+CpVbMkI9dk92OzU0vOBr40LnodAt47rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}