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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c280cc8aa77bb7940862be9bd9a0d4287b5cea1b065dcf9ffc438a7eb78ecfe' 
  AND token = 'Ez8I258b9WP29hhJ/JnpIViBlB9zuxFVmflvMIPyJbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}