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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5220a00a43e49db3200690f6448a5bab7883bc70c26aae419f94e5100ce280f2' 
  AND token = 'O7amBsTeON5zKCkvv0KKjbFUPVhSQQyYxecuJgzhGj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}