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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f86779549671b085aac615a6ab88f46bbcf60d2a91d314b396c190b20128ca' 
  AND token = 'QkRvFw905wt3Q0wa0bwfcK0x3R7qXBq5pGmk72pVZjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}