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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab527f24f271af96fe7d48e639fe5cfdd31e4eaeb9d52a3607abfdd36677db43' 
  AND token = 'WqV2roBmNK8sPLeoQHwTKOG+SBdWmxleTwASx6BuRTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}