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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68fd9e6f5cea5678bb9a9c52da16690c40823dc37911257767a50a1785744884' 
  AND token = 'DWmRHvDf2/8JlVwxHF2SS45doL5P0MWUKqokqloYNtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}