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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b91fd9960e3db158b71dc7605ce35c0b4c5fd65adc471427dfd600303ce1c3' 
  AND token = 'ujo0EBNwRR+uMmH58IGghfZlDPVY5mTyD0v3u+Pt5LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}