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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4726c62c39982c81ee83f769ed4e678e369be536fa58d3006c7491da63f8314' 
  AND token = 'iTwIqL/vB+7S2505FKDmbAGB+AV3bbXMELxQ7zrr0k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}