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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3eb50514f0e71c8cce486c1abbbc03ab72e75a0ed0fde42edb05fe14dee0fb3' 
  AND token = 'm41vB3P1pXRo6I9459Naw4Xl9LQWLkd8i0kVk4WpCJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}