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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23005fd934e098ec115693d51fe0c21e90698c482267d8b93bb6a246ff4e3e1c' 
  AND token = 'WpY7Paa7uxpd6HKUOps0wOdwM4OlnXEjPAjyxeaX2qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}