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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c5a2c87d4449095ccbe19fb7a1d24d96d09d0988d3b97968b0035be6e32cfc' 
  AND token = 'AWfMV1cl496kaISj+MwBlaE+/fSTkkMmcio9VAjF/qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}