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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6577c71a93dfad4cf4ca13050b31efa6d67d5a3afb1556d5744aa96df55550' 
  AND token = 'eX2ys1HiaJ8IBJqAwhnDpF87UryIKOFmUg89UCIAiCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}