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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ebb6a7187210b819ddb3a0fc9e4c168cb21f5c3e51d21a138ca8415b15f7eb0' 
  AND token = 'D1lYNz527VshiIVL+PcIrk5UgYoSyodOvLNU+EGDwWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}