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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fa6305ca13e9600172e3ee8306e5301aec882f38b221e8783f8150992675e39' 
  AND token = 'G8vxCjPG9K6HwFow5ycr4BrkCeKt+FPS0HUw6lk5+NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}