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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4b5b09a970b0544bcd9cbcea103da14b1eefa7a664e063e3b21d900bb2d1446' 
  AND token = 'IFvQ1y1hSQ5/GcsKn/IqglJnLKUq8B0VqrZYlLpWuIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}