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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720903c2a3160e2f7c75fd421454b95d1b3e3d46568c8f4be2bf4f2c4343be73' 
  AND token = 'V+BPgeLpPAfDtiFOtnYOGPD9pfhiEyBm6UjHBoo/OeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}