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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0876f4295fdd8265bdaf701ea47fc2e7baea0d0b35c5df97f8b72564c533de7a' 
  AND token = 'zG/gH8Wbw0d5bfYsWPQwFkMPWXOlF1wBODUfHyE0SH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}