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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eece1e014960dc6e9241d7599ecb47a4ec9225c934767e62d8b68b7aa7ad80f' 
  AND token = 'i25SIEbDr8ODNuupBzPlBmUY3NZB7OEY+nt4XOaFYZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}