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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e61ccfabcc33135eec0f961c70fb7c8a253566488a40407718d8a5d8917b1a9' 
  AND token = 'lSTAjz2k2Rd1RQLTEt0wD52AhX+BfRZYW07mwOIqcpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}