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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5d90de3d8d523af78ca21f5bdecc0f3648c1669861da7dba02d6836339679a' 
  AND token = 'CTzSKsioBnq1rw8t2pxDIU9syR9qTAwJPdS5bNjAIZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}