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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0766e2adb846060d912d26733cfc7ca444df044c4fc73b4ca648922dedd72b31' 
  AND token = 'NvW0BW6XrMqPOP/PCzQ1LlDsOaWsCip4dv5nL++uSNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}