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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385a18bf8891e0f26854d5c2f9b9de38c90ccf1288f39256c7328dac366e9b4b' 
  AND token = 'zeXY/tXW/3hSaXAYXZesvLW8GvE0pc4vMdhqaboFxmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}