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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f564a30e8300082f8e3e3df179d9dfa62b160c12a9c6d4c5c052c4754b4eae1' 
  AND token = 'dciI9h/tMMmVuiQer9HDiOdGAQQKHrKEnE1hl/+wYBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}