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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7a459c52f354f5e16e4cb83636d7ab6f13068052012a9ab48b7bbeb8751a5c3' 
  AND token = 'rUUm86IxpzcXPAKIW3wmEne2VghgqGTsEcvExKpy0ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}