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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e499edb8cd0bf47ff0db1298f4cd1cb9698086b8eda492db7b1cb8e3c784abd2' 
  AND token = 'pym7xya53zYg5YmQzyfF++Cy8n17igmNEBBL2VDtCEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}