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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72abc54b53d9d3b0f86b6edf8df2ddaecf1f1cb889e00faa7daf251b765a52e7' 
  AND token = 'zdZgLa0Y3Q42Ms+Dj3yM8dy+eSnv8zpXQLaGc7StEog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}