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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da60c8b6e14886c309f67953202d103820c9da425e6df9be12811a1ba23e3860' 
  AND token = 'hUlxLMLgTyhuuLvmmcuK8WcxAT7w+dB1UJZdHY122rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}