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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8089a01017a35ac378ec5e0d4fedcba5e4771c0f8b377b4fb1a11f40d70a5c2f' 
  AND token = 'RCwvKy4mkW7TGm1k3okCJ76yHY9BZuGDWS7CKIEuZIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}