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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db52a1107541de4f94164ef8418b55ab303c3bcfd237ab302a4e48da8cdfd14c' 
  AND token = 'IqRR/rmrYOtFZscCI42/ukzGge9XsLy5FvtJmMNIU5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}