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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec48896e02608ff2ce5618d68c521204dc472beccb441ff411cc88b44b71df8e' 
  AND token = '5+Xr+9uskNxPJpCyq9PEgdFTvytjzJX/NSJR44xPm0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}