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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0afbf7b2112d52f7cbf22db74885b2be3dec6600fd2bc100bea3b2d9d186f292' 
  AND token = 'r7hfRcqzXYfYnUX8vNKMddF+1TNY1r5uLRud3DkfLPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}