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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0629ce21892263578b9d42301f60b7fbd1e5d5f29720f98e4633b0004e476157' 
  AND token = 'PefLoVD9U6vARdnNt0Qszor9CnJAq+0a8mJ0+bifDVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}