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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc6c2bc5f86f49c55217fe3c961fce51a27c47f9adb1bead4d20d29890795f7' 
  AND token = '3nBtgDCjJjs8A7PKyBs1i6JaOeipxHaf+vUrwTwNaT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}