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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e08829bd340c9a1bb07f36bb80279c3a589ba6b252e8c64ae033f35eaaef1a8' 
  AND token = 'fk7CyUfte5nrbjwAA+seM0KAluslS/b4D4erpZ0ntV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}