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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c563a5aaa85f594443053cc72960c0b8fd21e8821b63d7d1bdc86d1a00cc3f1' 
  AND token = 'MTm+eTj8iNMDPI+XoQ7LlgEb00sVOPXXL4rGH11MUnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}