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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151aeb7c0066d48c8df05a62bb990c89c53cf4e9a3bce60a06920bf342128598' 
  AND token = 'Lz1/9Vs9iNgT6PBrHOB1jCAR7DznL09F9mJGx2mD4lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}