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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd5e133568470304e94796df4f8726b1dc6a075e99d3b0e75bc538f3f44cfd0e' 
  AND token = 'RxpiaOZP8iPkiG5ECDi/F9uridpdLaMP/pc2NqzOwPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}