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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f061cd9047c2bb059b601f715756c6418809297d6edfb60d6dfeb446670a704' 
  AND token = 'CL13G79w18/ZuUU6tIzhnOVvWrzXRyWspgEWY2uxxZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}