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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b2dfd5be55c9e9775f2e25beca0adbbe1c24d97e32836d412c1c70ca6aba49' 
  AND token = 'pdmasaEzC26Cbo8pYA2OPx9NB71ySl3LfcuEXaSsVpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}