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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332c1fc9e687d18cd3646bb6037f832438969a7d986f2a7888f70c4ea3c2d045' 
  AND token = 'XBt/FReowuFVaRyj9+1UdCTzwCm8WV5yUnVwm1hISwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}