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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc2bc225b6abec54192c157f77a1465d78bbc9d410a3790d67f5d2118603b9b4' 
  AND token = 'aVthqMBfJftqB18YuuQ+wtKGu4u+uMd6x0CJdEh+NLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}