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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e21d5bb2b62439b8d0f49f2f4292739261eef3bcde65feb1bfc9f54bc452de5' 
  AND token = 'NniM7AhVc2TYkdxbO5ZI69JxMst/Ldq+6D/sApUvFFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}