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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483859ef32cc93900f5cce667d8903c594e4c88f977ff7736c6ec484000b8f78' 
  AND token = 'c02Xaz/4V1cebRouLiXvmhyu7B6DxUH5KJT/1Jn+kLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}