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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e7dd7eeab0e42a3fd07a0ddcbf933bd5455d66854950f9d52c873807e8c32d9' 
  AND token = 'saOu0VQQvQuvJ7O6C0EyxX8Fxc6XdvGshUHYhkXf1D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}