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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a8914004629f40da957dc8b07691d064ce273e9ed5808c85da9d9960b7e300' 
  AND token = 'HIUj9gzWFXaAFrpqNEBDrWJjvA/3tWR3Sd/NPFd+B+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}